Approach to nasal tuberculosis in the outpatient setting: management and perspectives
DOI:
https://doi.org/10.18378/rebes.v14i1.10340Abstract
This article aims to analyze the management of nasal tuberculosis in an outpatient setting, with the aim of understanding current practices and identifying new perspectives for the treatment and follow-up of this condition. Tuberculosis is an infectious and globally prevalent disease caused by Mycobacterium tuberculosis, in which it typically presents with pulmonary manifestations, however, the incidence of cases with nasal involvement has aroused the interest of the medical community due to its diagnostic and therapeutic implications. In this context, the article focuses on the importance of early recognition and appropriate treatment of nasal tuberculosis, emphasizing the relevance of this approach in the outpatient setting, where most patients have their first contact with the health system. The methodology adopted consists of a literature review, in which scientific articles, case studies, and literature reviews published in the last ten years in reliable databases were selected and analyzed, allowing an up-to-date compilation of available information on nasal tuberculosis, covering aspects such as epidemiology, clinical manifestations, diagnostic methods, and therapeutic options. The results obtained from this review show that, although nasal tuberculosis is a less common form of the disease, its proper detection and management are essential to avoid complications and the spread of infection. It has been observed that the clinical manifestations of nasal tuberculosis are varied, which may lead to delays in diagnosis. In addition, the importance of specific diagnostic methods for this manifestation of the disease was highlighted, including imaging techniques and microbiological analyses. Regarding treatment, the studies analyzed point to the efficacy of the standard therapeutic regimen for tuberculosis, with adaptations according to the severity and specificities of each case.
Downloads
References
ACHARYA, B. et al. Advances in diagnosis of Tuberculosis: an update into molecular diagnosis of Mycobacterium tuberculosis. Molecular biology reports, v. 47, p. 4065-4075, 2020.
BANSAL, R.; JAIN, A.; MITTAL, S. Orofacial tuberculosis: Clinical manifestations, diagnosis and management. Journal of Family Medicine and Primary Care, v. 4, n. 3, p. 335, 2015.
BEHR, M. A.; EDELSTEIN, Paul H.; RAMAKRISHNAN, Lalita. Is Mycobacterium tuberculosis infection life long?. Bmj, v. 367, 2019.
CAMPELO, T. A. et al. Revisiting the methods for detecting Mycobacterium tuberculosis: what has the new millennium brought thus far?. Access Microbiology, v. 3, n. 8, p. 000245, 2021.
DADÁ, M. S.; SIDAT, M.; MALAGÓN, J. D. Tuberculose nasal: apresentação de um caso clínico. Muito obrigada a todos!, p. 52, 2018.
ESMAIL, H. et al. The immune response to Mycobacterium tuberculosis in HIV-1-coinfected persons. Annual review of immunology, v. 36, p. 603-638, 2018.
GETAHUN, H. et al. Latent Mycobacterium tuberculosis infection. New England Journal of Medicine, v. 372, n. 22, p. 2127-2135, 2015.
HOAGLAND, D. T. et al. New agents for the treatment of drug-resistant Mycobacterium tuberculosis. Advanced drug delivery reviews, v. 102, p. 55-72, 2016.
KHAN, S.; PUJANI, M.; JETLEY, S.. Primary nasal tuberculosis: Resurgence or coincidence− A report of four cases with review of literature. Journal of Laboratory Physicians, v. 9, n. 01, p. 026-030, 2017.
KOCH, A.; MIZRAHI, V. Mycobacterium tuberculosis. Trends in microbiology, v. 26, n. 6, p. 555-556, 2018.
KOZAKEVICH, G. V.; DA SILVA, R. M. Tuberculose: revisão de literatura. Arquivos Catarinenses de Medicina, v. 44, n. 4, p. 34-47, 2015.
MARTINO, M. et al. Immune response to Mycobacterium tuberculosis: a narrative review. Frontiers in pediatrics, v. 7, p. 350, 2019.
MILLER, T. et al. Global epidemiology of tuberculosis. In: Seminars in respiratory and critical care medicine. 333 Seventh Avenue, New York, NY 10001, USA.: Thieme Medical Publishers, 2018. p. 271-285.
MURRAY, J. F.; SCHRAUFNAGEL, D. E.; HOPEWELL, P. C. Treatment of tuberculosis. A historical perspective. Annals of the American Thoracic Society, v. 12, n. 12, p. 1749-1759, 2015.
RANGAKA, M. X. et al. Controlling the seedbeds of tuberculosis: diagnosis and treatment of tuberculosis infection. The Lancet, v. 386, n. 10010, p. 2344-2353, 2015.
SIA, J. K.; RENGARAJAN, J. Immunology of Mycobacterium tuberculosis infections. Microbiology spectrum, v. 7, n. 4, p. 10.1128/microbiolspec. gpp3-0022-2018, 2019.
SOTGIU, G. et al. Tuberculosis treatment and drug regimens. Cold Spring Harbor perspectives in medicine, v. 5, n. 5, 2015.
SRIVANITCHAPOOM, C. et al. Nasopharyngeal tuberculosis: epidemiology, mechanism of infection, clinical manifestations, and management. International journal of otolaryngology, v. 2016, 2016.
SUÁREZ, I. et al. The diagnosis and treatment of tuberculosis. Deutsches Aerzteblatt International, v. 116, n. 43, 2019.
SWAIN, S.; BEHERA, I.. A rare presentation of nasal tuberculosis. Journal of Medical Society, v. 34, n. 1, p. 47-47, 2020.
UZORKA, J. W. et al. Radiological signs of latent tuberculosis on chest radiography: a systematic review and meta-analysis. In: Open Forum Infectious Diseases. US: Oxford University Press, 2019. p. ofz313.
ZHANG, Y.; YEW, W. W. Mechanisms of drug resistance in Mycobacterium tuberculosis: update 2015. The International Journal of Tuberculosis and Lung Disease, v. 19, n. 11, p. 1276-1289, 2015.
Downloads
Published
Versions
- 2024-02-01 (2)
- 2024-02-01 (1)
How to Cite
Issue
Section
License
Copyright (c) 2024 Karina dos Santos Alencastro, Bruna Bezerra Torres de Sá, Mariana Fonseca Vilela, Maria de Fátima Ortega Kroling, Andressa Aline Valente de Moura, Tarcys Barbosa da Silva, Rarissa Brito Dourado, Mário Pinheiro Esposito
This work is licensed under a Creative Commons Attribution 4.0 International License.
Termo de cess