Exploring Cervical Lymphadenitis in Children: PFAPA as a challenge in differential diagnosis – a rare or unknown disease?
DOI:
https://doi.org/10.18378/rebes.v14i1.10342Abstract
Cervical lymphadenitis is an inflammation of the lymph nodes located in the neck region and occurs predominantly in children of both sexes, and may be related to other diseases, rarely presenting in isolation. With this in mind, the general objective of this article is to analyze and elucidate Cervical Lymphadenitis in children, focusing on PFAPA Syndrome, highlighting its characteristics, challenges in differential diagnosis and questioning whether this condition is a rare disease or still little recognized by the medical community. The methodology used was the literary search in databases such as SCIELO and LILACS, using the following descriptors: PFAPA, cervical lymphadenitis and children; The selected articles were published in full in Portuguese and English, in the years 2016 to 2023. After analyzing the materials, it can be concluded that lymphadenitis can be originated by viruses or bacteria and are better identified in childhood, which allows the applicability of more efficient interventions and treatments, according to the patient's needs.
Downloads
References
ADROVIC, Amra et al. Familial Mediterranean fever and periodic fever, aphthous stomatitis, pharyngitis, and adenitis (PFAPA) syndrome: shared features and main differences. Rheumatologyinternational, v. 39, n. 1, p. 29-36, 2019.
AKTAS, Ozturk et al. Acompanhamento em longo prazo da eficácia da tonsilectomia em crianças com síndrome de PFAPA☆. Brazilian Journal of Otorhinolaryngology, v. 85, p. 78-82, 2019.
BATU, EzgiDeniz. Periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) syndrome: main features and an algorithm for clinical practice. Rheumatologyinternational, v. 39, n. 6, p. 957-970, 2019.
BUENO, Laniel Aparecido; PAIVA, Débora Magalhães; DE CARVALHO, Paulo Henrique Pimenta. Síndrome PFAPA: Diagnóstico e Tratamento na Atenção Primária à Saúde. Revista Brasileira de Medicina de Família e Comunidade, v. 14, n. 41, p. 1815-1815, 2019.
CANTARINI, Luca et al. Diagnostic criteria for adult-onset periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) syndrome. Frontiers in Immunology, v. 8, p. 1018, 2017.
HOFER, Michaël. Why and how should we treat periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) syndrome?. PediatricDrugs, v. 22, n. 3, p. 243-250, 2020.
MENDONÇA, Leonardo Oliveira et al. Síndrome PFAPA (febre periódica, aftas orais, faringite e adenite cervical) em crianças e adultos. Arquivos de Asma, Alergia e Imunologia, v. 3, n. 1, p. 29-36, 2019.
NEVES, Lucas; ANDRADE, Ana; CASTRO; Carla; ARAÚJO, Fábio; BRITO, Felipe; MACIEL, Fernando; MACEDO, Rômulo. Tuberculose ganglionar em paciente pediátrico: relato de caso clínico. 2023.
RENKO, Marjo; LANTTO, Ulla; TAPIAINEN, Terhi. Towards better diagnostic criteria for periodic fever, aphthous stomatitis, pharyngitis and adenitis syndrome. ActaPaediatrica, v. 108, n. 8, p. 1385-1392, 2019.
RYDENMAN, Karin et al. PFAPA syndrome-An important differential diagnosis in children with recurrent fever. Lakartidningen, v. 116, 2019.
SILBER, Fabio Wainstein; SILBER, Marcelo; SANTO, Douglas Alexandre Espírito. Síndrome PFAPA e as febres periódicas da infância: relato de caso. Revista da Faculdade de Ciências Médicas de Sorocaba, v. 19, n. 4, p. 227-231, 2017.
Downloads
Published
Versions
- 2024-02-05 (2)
- 2024-02-05 (1)
How to Cite
Issue
Section
License
Copyright (c) 2024 Cicera Kaline Gomes Barreto, Thaise de Abreu Brasileiro Sarmento, João Pedro Pereira da Silva
![Creative Commons License](http://i.creativecommons.org/l/by/4.0/88x31.png)
This work is licensed under a Creative Commons Attribution 4.0 International License.
Termo de cess